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1

Intrapatient and Interpatient Pharmacokinetic Variability of Raltegravir in the Clinical Setting

Siccardi, Marco, DʼAvolio, Antonio, Rodriguez-Novoa, Sonia, Cuenca, Lorena, Simiele, Marco, Baietto, Lorena, Calcagno, Andrea, Moss, Darren, Bonora, Stefano, Soriano, Vicente, Back, David J., Owen, An

Journal:

Therapeutic Drug Monitoring

Year:

2012

Language:

english

File:

PDF, 110 KB

english, 2012

2

Impairment in kidney tubular function in patients receiving tenofovir is associated with higher tenofovir plasma concentrations

Rodríguez-Nóvoa, Sonia, Labarga, Pablo, DʼAvolio, Antonio, Barreiro, Pablo, Albalate, Marta, Vispo, Eugenia, Solera, Carmen, Siccardi, Marco, Bonora, Stefano, Di Perri, Giovanni, Soriano, Vincent

Journal:

Year:

2010

Language:

english

File:

PDF, 302 KB

english, 2010

3

Kidney tubular abnormalities in HIV patients treated with tenofovir with normal glomerular function – results of a prospective study on 284 patients

P Labarga, P Barreiro, L Martin-Carbonero, S Rodríguez-Nóvoa, C Solera, J Medrano, P Rivas, M Albalate, F Blanco, V Moreno, E Vispo, E Valencia, J González-Lahoz, V Soriano

Journal:

Journal of the International AIDS Society

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008

4

Raltegravir: a potent and safe integrase inhibitor with a favourable impact on cardiovascular and liver profile

F Blanco, M Arredondo, F Guevara, C Garrido, J Morello, S Rodríguez-Nóvoa, M Córdoba, J González-Lahoz, V Soriano

Journal:

Journal of the International AIDS Society

Year:

2008

Language:

english

File:

PDF, 108 KB

english, 2008

5

Simplification from TPV/RTV 500/200 BID to TPV/RTV 500/100 BID guided by therapeutic drug monitoring

J Morello, S Rodríguez-Nóvoa, F Blanco, I Jiménez-Nácher, G González-Pardo, AJ Rubio, V Soriano

Journal:

Journal of the International AIDS Society

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

6

Hepatitis C virus (HCV) treatment uptake and changes in the prevalence of HCV genotypes in HIV/HCV-coinfected patients

J. Medrano, S. Resino, E. Vispo, A. Madejón, P. Labarga, P. Tuma, L. Martín-Carbonero, P. Barreiro, S. Rodriguez-Novoa, I. Jiménez-Nacher, V. Soriano

Journal:

Journal of Viral Hepatitis

Year:

2011

Language:

english

File:

PDF, 469 KB

english, 2011

7

Overview of the pharmacogenetics of HIV therapy

Rodríguez-Nóvoa, S, Barreiro, P, Jiménez-Nácher, I, Soriano, V

Journal:

The Pharmacogenomics Journal

Year:

2006

Language:

english

File:

PDF, 436 KB

english, 2006

8

801 RESCUE THERAPY WITH OPTIMIZED PEG-INTERFERON PLUS RIBAVIRIN IN HIV/HCV COINFECTED PATIENTS: CRITICAL ROLE OF RIBAVIRIN PLASMA LEVELS IN THE PILOT-NR TRIAL

P. Labarga, M.E. Vispo, P. Barreiro, J. García-Samaniego, S. Rodriguez-Novoa, J. Morello, J. Pinilla, L. Martin-Carbonero, J. Troya, J. Gonzalez-Lahoz, V. Soriano

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

9

838 DISTINCT HEPATITIS C VIRUS KINETICS IN HIV+ PATIENTS TREATED WITH RIBAVIRIN PLUS EITHER PEGYLATED INTERFERON ALFA-2A OR ALFA-2B

E. Vispo, P. Barreiro, S. Rodríguez-Novoa, J. Morello, P. Labarga, L. Martín-Carbonero, I. Maida, P. García-Gascó, V. Soriano

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

10

648 DIFFERENCES IN ANTIVIRAL ACTIVITY AND TOLERABILITY BETWEEN PEGYLATED INTERFERON ALPHA – 2A AND – 2B IN HIV INFECTED PATIENTS WITH CHRONIC HEPATITIS C

E. Vispo, P. Tuma, J. Medrano, P. Barreiro, S. Rodriguez-Novoa, J. Morello, P. Labarga, L. Martin-Carbonero, V. Soriano

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 69 KB

english, 2009

11

282 A SPECIFIC HAPLOTYPE AT THE ENT1 GENE INFLUENCES THE RATE OF SUSTAINED VIROLOGICAL RESPONSE TO PEGINTERFERON-RIBAVIRIN IN HIV/HCV-COINFECTED PATIENTS

J. Morello, L. Cuenca, V. Soriano, J. Medrano, G. González-Pardo, E. Álvarez, A. Madejón, J. González-Lahoz, S. Rodríguez-Nóvoa

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 52 KB

english, 2010

12

Antivirales

S. Rodríguez-Nóvoa, I. Jiménez-Nácher, P. Barreiro

Journal:

Medicine - Programa de Formación Médica Continuada Acreditado (Elsevier España)

Year:

2006

File:

PDF, 102 KB

2006

13

Antirretrovirales

P. Barreiro, N. Simarro, S. Rodríguez-Nóvoa

Journal:

Medicine - Programa de Formación Médica Continuada Acreditado (Elsevier España)

Year:

2006

File:

PDF, 237 KB

2006

14

Farmacogenética de la respuesta al tratamiento antirretroviral

Sonia Rodríguez-Nóvoa, Vicente Soriano Vázquez

Journal:

Enfermedades Infecciosas y Microbiología Clínica

Year:

2008

File:

PDF, 385 KB

2008

15

Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia in HIV/HCV-Coinfected Patients With All HCV Genotypes

Naggie, S., Rallon, N. I., Benito, J. M., Morello, J., Rodriguez-Novoa, S., Clark, P. J., Thompson, A. J., Shianna, K. V., Vispo, E., McHutchison, J. G., Goldstein, D. B., Soriano, V.

Journal:

The Journal of Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 204 KB

english, 2012

16

Uso combinado de amplificación aleatoria de polimorfismo del ADN (RAPD) y reacción en cadena de la polimerasa (touchdown PCR) en el estudio epidemiológico de Aspergillus fumigatus

Treviño-Castellano, Mercedes, Rodríguez-Nóvoa, Sonia, Llovo-Taboada, José, García-Zabarte, Ángeles, García-Riestra, Carlos, José Regueiro-García, Benito

Journal:

Enfermedades Infecciosas y Microbiología Clínica

Year:

2003

File:

PDF, 81 KB

2003

17

832 MONITORING OF FACTORS RELATED TO PLASMA CONCENTRATION OF RIBAVIRIN COULD IMPROVE RESPONSE TO ANTIVIRAL THERAPY IN CHRONIC HEPATITIS C GENOTYPE 1

Jiménez Macías, F.M., Rodríguez-Novoa, S., Alvárez Barco, E., Morello Bullón, J., Ferna'ndez Codejón, O., Barrero Alor, F., Ramos Lora, M., Galisteo Almeda, L., Ruíz-Frutos, C., Pujol de la Llave, E.,

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 176 KB

english, 2013

18

1008 KIDNEY TUBULAR DYSFUNCTION (KTD) IN PATIENTS WITH PROLONGED EXPOSURE TO TENOFOVIR (TDF): A PROSPECTIVE STUDY

Labarga, P., Barreiro, P., Rodriguez-Novoa, S., Vispo, E., Albalate, M., Martín-Carbonero, L., Solera, C., Medrano, J., Blanco, F., Soriano, V.

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 51 KB

english, 2010

19

1160 HEPATIC SAFETY PROFILE OF NEW ANTIRETROVIRAL DRUGS IN HIV-INFECTED PATIENTS WITH CHRONIC HEPATITIS C

Vispo, E., Mena, A., Maida, I., Blanco, F., Córdoba, M., Labarga, P., Rodriguez-Novoa, S., Alvarez, E., Jimenez-Nacher, I., Soriano, V.

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 96 KB

english, 2010

20

Influence of 516G>T Polymorphisms at the Gene Encoding the CYP450-2B6 Isoenzyme on Efavirenz Plasma Concentrations in HIV-Infected Subjects

Rodriguez-Novoa, S., Barreiro, P., Rendon, A., Jimenez-Nacher, I., Gonzalez-Lahoz, J., Soriano, V.

Journal:

Clinical Infectious Diseases

Year:

2005

Language:

english

File:

PDF, 95 KB

english, 2005

21

Approaches for understanding and predicting drug interactions in human immunodeficiency virus-infected patients

Jiménez-Nácher, Inmaculada, Alvarez, Elena, Morello, Judit, Rodriguez-Nóvoa, Sonia, de Andrés, Susana, Soriano, Vincent

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

22

Short Communication: Association between Tipranavir Plasma Levels and Virological Response in HIV-Infected Patients

Morello, Judit, Gascó, Pilar Garcia, Rodriguez-Novoa, Sonia, de Mendoza, Carmen, Blanco, Francisco, Gonzalez-Pardo, Gema, Sanz, Beatriz, Jimenez-Nacher, Inmaculada, Soriano, Vincent

Journal:

AIDS Research and Human Retroviruses

Year:

2008

Language:

english

File:

PDF, 84 KB

english, 2008

23

Value of the HLA-B*5701 Allele to Predict Abacavir Hypersensitivity in Spaniards

Rodríguez-Nóvoa, Sonia, García-Gascó, Pilar, Blanco, Francisco, González-Pardo, Gema, Castellares, Carol, Moreno, Victoria, Jiménez-Nácher, Inmaculada, González-Lahoz, Juan, Soriano, Vincent

Journal:

AIDS Research and Human Retroviruses

Year:

2007

Language:

english

File:

PDF, 53 KB

english, 2007

24

Preemptive Erythropoietin Plus High Ribavirin Doses to Increase Rapid Virological Responses in HIV Patients Treated for Chronic Hepatitis C

Vispo, Eugenia, Labarga, Pablo, Guardiola, Josep M., Barreiro, Pablo, Miralles, Celia, Rubio, Rafael, Miralles, Pilar, Aguirrebengoa, Koldo, Portu, Joseba, Morello, Judit, Rodriguez-Novoa, Sonia, Sori

Journal:

AIDS Research and Human Retroviruses

Year:

2010

Language:

english

File:

PDF, 142 KB

english, 2010

25

Higher Risk of Hyperglycemia in HIV-Infected Patients Treated with Didanosine Plus Tenofovir

García-Benayas, Teresa, Rendón, Ana Lucía, Rodríguez-Novóa, Sonia, Barrios, Ana, Maida, Ivana, Blanco, Francisco, Barreiro, Pablo, Rivas, Pablo, González-Lahoz, Juan, Soriano, Vincent

Journal:

AIDS Research and Human Retroviruses

Year:

2006

Language:

english

File:

PDF, 137 KB

english, 2006

26

Short Communication: Use of Serum Bilirubin Levels as Surrogate Marker of Early Virological Response to Atazanavir-Based Antiretroviral Therapy

Morello, Judit, Álvarez, Elena, Cuenca, Lorena, Vispo, Eugenia, González-Lahoz, Juan, Soriano, Vincent, Rodríguez-Nóvoa, Sonia

Journal:

AIDS Research and Human Retroviruses

Year:

2011

Language:

english

File:

PDF, 99 KB

english, 2011

27

Efficacy and Safety of a Once Daily Regimen with Efavirenz, Lamivudine, and Didanosine, with and without Food, as Initial Therapy for HIV Infection: The ELADI Study

Sánchez-Conde, Matilde, Palacios, Rosario, Sanz, José, Rodríguez-Novoa, Sonia, Rivas, Pablo, Santos, Jesús, Sola, Julio, Asensi, Victor, de Mendoza, Carmen, Estrada, Vicente, Barreiro, Pablo, González

Journal:

AIDS Research and Human Retroviruses

Year:

2007

Language:

english

File:

PDF, 66 KB

english, 2007

28

Switch from Ritonavir-Boosted to Unboosted Atazanavir Guided by Therapeutic Drug Monitoring

Rodríguez-Nóvoa, Sonia, Morello, Judit, Barreiro, Pablo, Maida, Ivana, García-Gascó, Pilar, Vispo, Eugenia, González-Pardo, Gema, Parra, Antonio, Jiménez-Nácher, Inmaculada, Soriano, Vincent

Journal:

AIDS Research and Human Retroviruses

Year:

2008

Language:

english

File:

PDF, 209 KB

english, 2008

29

Efficacy and safety of replacing lopinavir with atazanavir in HIV-infected patients with undetectable plasma viraemia: final results of the SLOAT trial

Soriano, V., Garcia-Gasco, P., Vispo, E., Ruiz-Sancho, A., Blanco, F., Martin-Carbonero, L., Rodriguez-Novoa, S., Morello, J., de Mendoza, C., Rivas, P., Barreiro, P., Gonzalez-Lahoz, J.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2007

Language:

english

File:

PDF, 147 KB

english, 2007

30

Plasma Raltegravir Exposure Influences the Antiviral Activity and Selection of Resistance Mutations

Garrido, Carolina, de Mendoza, Carmen, Álvarez, Elena, García, Federico, Morello, Judit, Garcia, Silvia, Ribera, Esteban, Rodríguez-Novoa, Sonia, Gutierrez, Felix, Soriano, on behalf of the SinRES Te,

Journal:

AIDS Research and Human Retroviruses

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

31

Pharmacogenetics of tenofovir treatment

Rodriguez-Novoa, Sonia, Labarga, Pablo, Soriano, Vincent

Journal:

Pharmacogenomics

Year:

2009

Language:

english

File:

PDF, 1.50 MB

english, 2009

32

Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements

Jimenez-Nacher, I., Garcia, B., Barreiro, P., Rodriguez-Novoa, S., Morello, J., Gonzalez-Lahoz, J., de Mendoza, C., Soriano, V.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2008

Language:

english

File:

PDF, 248 KB

english, 2008

33

Plasma Ribavirin Trough Concentrations at Week 4 Predict Hepatitis C Virus (HCV) Relapse in HIV-HCV-Coinfected Patients Treated for Chronic Hepatitis C

Morello, J., Soriano, V., Barreiro, P., Medrano, J., Madejon, A., Gonzalez-Pardo, G., Jimenez-Nacher, I., Gonzalez-Lahoz, J., Rodriguez-Novoa, S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 142 KB

english, 2010

34

Use of the HCP5 single nucleotide polymorphism to predict hypersensitivity reactions to abacavir: correlation with HLA-B*5701

Rodriguez-Novoa, S., Cuenca, L., Morello, J., Cordoba, M., Blanco, F., Jimenez-Nacher, I., Soriano, V.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2010

Language:

english

File:

PDF, 126 KB

english, 2010

35

Kidney tubular abnormalities in the absence of impaired glomerular function in HIV patients treated with tenofovir

Labarga, Pablo, Barreiro, Pablo, Martin-Carbonero, Luz, Rodriguez-Novoa, Sonia, Solera, Carmen, Medrano, Jose, Rivas, Pablo, Albalater, Marta, Blanco, Francisco, Moreno, Victoria, Vispo, Eugenia, Sori

Journal:

Year:

2009

Language:

english

File:

PDF, 131 KB

english, 2009

36

Impact of Inosine Triphosphatase Gene Variants on the Risk of Anemia in HIV/Hepatitis C Virus-Coinfected Patients Treated for Chronic Hepatitis C

Rallon, N. I., Morello, J., Labarga, P., Benito, J. M., Rodriguez-Novoa, S., Vispo, E., Barreiro, P., Castro, M. A., Aguirrebengoa, K., Pineda, J. A., Miralles, P., Tellez, M. J., Portu, J., Miralles,

Journal:

Clinical Infectious Diseases

Year:

2011

Language:

english

File:

PDF, 221 KB

english, 2011

37

Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction

Pushpakom, S. P., Liptrott, N. J., Rodriguez-Novoa, S., Labarga, P., Soriano, V., Albalater, M., Hopper-Borge, E., Bonora, S., Di Perri, G., Back, D. J., Khoo, S., Pirmohamed, M., Owen, A.

Journal:

The Journal of Infectious Diseases

Year:

2011

Language:

english

File:

PDF, 308 KB

english, 2011

38

Use of Different Inhibitory Quotients To Predict Early Virological Response to Tipranavir in Antiretroviral-Experienced Human Immunodeficiency Virus-Infected Patients

Morello, J., De Mendoza, C., Soriano, V., Anta, L., Gonzalez-Pardo, G., Corral, A., Blanco, F., Jimenez-Nacher, I., Gonzalez-Lahoz, J., Rodriguez-Novoa, S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 69 KB

english, 2009

39

Usefulness of monitoring ribavirin plasma concentrations to improve treatment response in patients with chronic hepatitis C

Morello, J., Rodriguez-Novoa, S., Jimenez-Nacher, I., Soriano, V.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

40

Hepatic safety profile of raltegravir in HIV-infected patients with chronic hepatitis C

Vispo, E., Mena, A., Maida, I., Blanco, F., Cordoba, M., Labarga, P., Rodriguez-Novoa, S., Alvarez, E., Jimenez-Nacher, I., Soriano, V.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2010

Language:

english

File:

PDF, 214 KB

english, 2010

41

Current trends in screening across ethnicities for hypersensitivity to abacavir

Rodriguez-Nóvoa, Sonia, Soriano, Vincent

Journal:

Pharmacogenomics

Year:

2008

Language:

english

File:

PDF, 1.53 MB

english, 2008

42

Differences in Lopinavir Plasma Concentrations Comparing Kaletra® Film Coated Tablets and Soft Gelatine Capsules That Result in Various Lipid Abnormalities

Morello, Judit, Soriano, Vincent, Blanco, Francisco, Rubio, Antonio, Jimenez-Nacher, Inmaculada, Rodriguez-Novoa, Sonia

Journal:

Drug Metabolism Letters

Year:

2009

Language:

english

File:

PDF, 53 KB

english, 2009

43

Tipranavir: a new protease inhibitor for the treatment of antiretroviral-experienced HIV-infected patients

de Mendoza, Carmen, Morelló, Judit, Garcia-Gascó, Pilar, Rodríguez-Novoa, Sonia, Soriano, Vincent

Journal:

Expert Opinion on Pharmacotherapy

Year:

2007

Language:

english

File:

PDF, 399 KB

english, 2007

44

Drug Interactions of Tipranavir, a New HIV Protease Inhibitor

Morello, Judit, Rodriguez-Novoa, Sonia, Jimenez-Nacher, Inmaculada, Soriano, Vincent

Journal:

Drug Metabolism Letters

Year:

2007

Language:

english

File:

PDF, 82 KB

english, 2007

45

RETRACTED ARTICLE: Simplification From Protease Inhibitors to Once- or Twice-Daily Raltegravir: The ODIS Trial

Vispo, Eugenia, Barreiro, Pablo, Maida, Ivana, Mena, Alvaro, Blanco, Francisco, Rodríguez-Novoa, Sonia, Morello, Judit, Jimenez-Nacher, Inmaculada, Gonzalez-Lahoz, Juan, Soriano, Vincent

Journal:

HIV Clinical Trials

Year:

2010

File:

PDF, 49 KB

2010

46

Atazanavir: The Advent of a New Generation of More Convenient Protease Inhibitors

Pablo, Barreiro, Ana, Rendón, Sonia, Rodríguez-Nóvoa, Vincent, Soriano

Journal:

HIV Clinical Trials

Year:

2005

Language:

english

File:

PDF, 124 KB

english, 2005

47

Mitochondrial DNA depletion in HIV-infected patients with chronic hepatitis C and effect of pegylated interferon plus ribavirin therapy

de Mendoza, Carmen, Martin-Carbonero, Luz, Barreiro, Pablo, de Baar, Michel, Zahonero, Natalia, Rodriguez-Novoa, Sonia, Benito, José Miguel, González-Lahoz, Juan, Soriano, Vincent

Journal:

Year:

2007

Language:

english

File:

PDF, 99 KB

english, 2007

48

Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia

Rodríguez-Nóvoa, Sonia, Martín-Carbonero, Luz, Barreiro, Pablo, González-Pardo, Gema, Jiménez-Nácher, Inmaculada, González-Lahoz, Juan, Soriano, Vincent

Journal:

Year:

2007

Language:

english

File:

PDF, 99 KB

english, 2007

49

Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV–hepatitis C virus-coinfected patients with prior nonresponse or relapse

Labarga, Pablo, Barreiro, Pablo, Mira, José A, Vispo, Eugenia, Rallón, Norma, Neukam, Karin, Camacho, Angela, Caruz, Antonio, Rodriguez-Novoa, Sonia, Pinilla, Javier, Rivero, Antonio, Benito, José M,

Journal:

Year:

2011

Language:

english

File:

PDF, 332 KB

english, 2011

50

Increase in serum bilirubin in HIV/hepatitis-C virus-coinfected patients on atazanavir therapy following initiation of pegylated-interferon and ribavirin

Rodríguez-Nóvoa, Sonia, Morello, Judit, González, Mar, Vispo, Eugenia, Barreiro, Pablo, González-Pardo, Gema, Jiménez-Nácher, Inmaculada, Gonzalez-Lahoz, Juan, Soriano, Vincent

Journal:

Year:

2008

Language:

english

File:

PDF, 361 KB

english, 2008